PT-141 (Bremelanotide) is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH) and a non-selective melanocortin receptor agonist. It is commonly studied for its central nervous system interactions with melanocortin receptor subtypes (MC1R–MC5R) and their roles in neuroendocrine and autonomic signaling.
- Commonly studied for its agonist activity at melanocortin receptor subtypes, particularly MC3R and MC4R, in CNS signaling research
- Associated with research into hypothalamic regulation of autonomic nervous system pathways and neuroendocrine feedback loops
- May support research into the role of melanocortin signaling in inflammation modulation and immune cell biology
- Observed in studies examining blood pressure and cardiovascular autonomic response in melanocortin pathway research
- Frequently referenced in research exploring the central melanocortin system's role in energy homeostasis and reward circuitry
For Research Use Only. This compound is intended exclusively for in-vitro laboratory research by qualified investigators. It is not intended for human or animal consumption, is not a pharmaceutical product, and has not been evaluated by the FDA for safety or efficacy.
Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

